Project Discovery: Human Protein Atlas: Difference between revisions

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 | Aggresome || The aggresome can be seen as a very dense, oval ball next to the nucleus (blue marker). It overlaps with a hole in the microtubules (red marker). || [[File:PDAggresome.png]]
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-| Mitochondria || Example || Example
+| Mitochondria || A thread like pattern, rather like spaghetti (sometimes long and sometimes chopped up). The mitochondria can be found throughout the cell, starting centrally, close to the nucleus and stretch all the way out to the edges of the cell. || [[File:PDMitochondria.png]]
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-| Rods and rings || Example || Example
+| Rods and rings || Small and distinct rod and ring-like structures, usually only one or a few per cell. || [[File:PDRodsandrings.png]]
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-| Cytoskeleton (intermediate filaments) || Example || Example
+| Cytoskeleton (intermediate filaments) || Often seen as tangled, rope-like structure throughout the cell. Some are smaller and enclose the nucleus (blue marker), and have a more condensed look. || Example
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-| Cytoskeleton (microtubule ends) || Example || Example
+| Cytoskeleton (microtubule ends) || Short strands at the tip or the center of the microtubules (red marker), overlapping perfectly with it. Sometimes only the ends are stained and not the rest of the microtubules. || Example
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-| Cytoskeleton (microtubules) || Example || Example
+| Cytoskeleton (microtubules) || Thin strands stretching throughout the cell. Overlaps perfectly with the red marker making the colour turn yellow. || Example
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-| Cytoskeleton (actin filaments) || Example || Example
+| Cytoskeleton (actin filaments) || Long, very straight and parallel filaments that outline the edges of the cell. || Example
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-| Cytoskeleton (cytokinetic bridge) || Example || Example
+| Cytoskeleton (cytokinetic bridge) || A small structure that can only be seen at the tip between two cells that have almost been separated and moved apart, next to condensed microtubules (red marker).  || Example
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-| Microtubule organizing center || Example || Example
+| Microtubule organizing center || A small and somewhat diffuse structure that overlaps with the center of the microtubules (red marker), next to the nucleus (blue marker). || Example
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-| Centrosome || Example || Example
+| Centrosome || Single or double spots which overlaps witht he center of the microtubules (red marker), next to the nucleus (blue marker). || Example
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-| Endoplasmic reticulum || Example || Example
+| Endoplasmic reticulum || A symmetrical structure found throughout the cell (excluded from the blue marker). It is a mesh like network that looks somewhat like a spider's web. || Example
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-| The Golgi apparatus || Example || Example
+| The Golgi apparatus || The Golgi apparatus is located next to the nucleus, sometimes lying around or above it. It often looks like a collection of small, dense particles that may be donut shaped. || Example
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-| Vesicles || Example || Example
+| Vesicles || Small, bright dots that are uniform in size and shape. They are either evenly distributed throughout the cell, or clustering next to the nucleus (blue marker) but never in the nucleus. || Example
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-| Cell junctions || Example || Example
+| Cell junctions || Can only be observed when the cells are in contact, at the actual site of cell-cell connections. || Example
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-| Focal adhesions || Example || Example
+| Focal adhesions || Located under the cell or at the edge of the cell membrane, where the cell is attached to the surface. || Example
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-| Plasma membrane || Example || Example
+| Plasma membrane || It may appear as a uniform and very flat staining across the entire cell, and can usually be seen clearly outside the red marker. Sometimes only appears as a rim around the cell, and sometimes protrusions are extending from it. || Example
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 | Cell-to-cell variations || Example || Example